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Monkeypox (MPX) outbreak 2022 | SCDHEC

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Updated August 22, 2022

DHEC is responding to the 2022 monkeypox virus (MPX) outbreak in the United States to ensure the health and safety of all South Carolina residents. We are following CDC guidelines to monitor known patient contacts and identify anyone infected in our state. DHEC vaccinates those most at risk to stop the potential spread of the virus. Learn more about DHEC’s response efforts.

Latest case counts, vaccinations

DHEC reports confirmed cases of MPX to the US Centers of Disease Control and Prevention (CDC) daily; see the CDC’s MPX tracking map for current cases by state. Every Friday, DHEC also provides a regional breakdown of cases in South Carolina. Since Friday August 19, there have been 80 MPX cases reported in South Carolina:

  • 22 case in the Lowcountry,
  • 29 case in the Midlands,
  • 5 cases in the Pee Dee and,
  • 24 case in the upstate.

DHEC responds to these cases and vaccinates high-risk contacts with a safe, FDA-approved vaccine for MPX. To date, South Carolina has received 4,287 Jynneos vaccine doses from the federal government and donated 648 total vaccinations.

The Jynneos vaccine is available at DHEC clinics for those most at risk of exposure. People can call the DHEC CareLine (855) 472-3432 to find out if they are eligible to make an appointment. The vaccine is not recommended for the general public or healthcare workers at this time.

Unlike COVID-19 or other viruses that pose a greater threat to the public, MPX vaccinations are not currently recommended for the general population due to the specific way the virus spreads. They are currently only recommended for people in high-risk groups.

Educational material

The public, community partners, healthcare providers and others can share these materials to help raise awareness and reduce exposure to MPX in South Carolina.

What you need to know about MPX

MPX is a rare but potentially serious viral illness that usually begins with flu-like symptoms and swollen lymph nodes and progresses to a rash on the face and body. Most infections last two to four weeks. MPX, is a reportable condition in South Carolina as a new infectious agent.

MPX spreads between people primarily through direct contact with infectious wounds, scabs, or bodily fluids. MPX can be spread through intimate contact between people, including sex, kissing, cuddling, or close conversation; and touching fabrics and objects that have been used by someone with MPX, such as bedding and towels. It can also be spread through the cough or saliva of someone with MPX.

  • Painful rash
  • Fever
  • Headache
  • Muscle aches
  • Swollen lymph nodes

Symptoms usually appear 7 to 14 days after exposure.

Visuals CDC Monkeypox

If you are concerned that you have MPX or have had prolonged close contact with someone who has been diagnosed with MPX, please speak with your usual health care provider or, if you do not have one, call your local health department or emergency service.

At this time, the risk to the general public is low. Currently, the vast majority of cases occur in gay and bisexual men. However, anyone who has prolonged skin-to-skin contact with someone with MPX is at risk of becoming infected.

Key information for clinical providers

August 3, 2022: Dr. Linda Bell Provides MPX Information to Our State’s Health Care Providers
  • If you suspect MPX in a patient, after your assessment, please report it to your regional DHEC epidemiology team. DHEC can initiate contact tracing while awaiting lab results for highly probable cases and provide further guidance.
  • Testing for MPX is available through commercial laboratories or the Public Health Laboratory. PHL tests require prior approval but have a faster turnaround time. See HAN: Updated guidelines for assessment of Monkeypox virus (MPXV) (7-06-2022).
  • For people with severe cases of MPX, DHEC has pre-positioned TPOXX antiviral treatment statewide. Please consult the DHEC medical consultant covering your region to obtain the TPOXX for a patient. Do not call the CDC directly.

low country

Allendale, Bamberg, Beaufort,
Berkeley, Calhoun, Charleston,
Colleton, Dorchester, Hampton,
Jasper, Orangeburg

4050 Bridge View Drive, Suite 600
N. Charleston, SC 29405

Office: (843) 441-1091
Fax: (843) 953-0051
Nights/weekends: (843) 441-1091


Aiken, Barnwell, Chester,
Edgefield, Fairfield, Lancaster,
Lexington, Kershaw, Newberry,
Richland, Saluda, York

2000 Hampton Street
Columbia, South Carolina 29204

Office: (888) 801-1046
Fax: (803) 576-2993
Nights/weekends: (888) 801-1046


Clarendon, Chesterfield,
Darlington, Dillon, Florence,
Georgetown, Horry, Lee, Marion,
Marlboro, Sumter, Williamsburg

1931 Industrial Park Road
Conway, SC 29526

Office: (843) 915-8886
Fax: (843) 915-6506
Nights/weekends: (843) 409-0695


Abbeville, Anderson, Cherokee,
Greenville, Greenwood, Laurens,
McCormick, Oconee, Pickens,
Spartanburg, Union

352 Halton Road
Greenville, SC 29607

Office: (864) 372-3133
Fax: (864) 282-4373
Nights/weekends: (864) 423-6648

  • See previously published HANs:

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